Figure 12

Increase in binding rate and decrease in dissociation rate increase GPVI dimerisation. Simulation varying the binding and dissociation rate value from −40%, −30%, …, + 30%, + 40%, deviating from the initial values of kb = 0.05 molecule–1 unit time–1 and kd = 0.01 unit time–1. Values represent percentages of GPVI in dimeric form, as a proportion of total GPVI. Red colour represents higher dimerisation, blue lower dimerisation.