Figure 4 | Scientific Reports

Figure 4

From: An agent-based approach for modelling and simulation of glycoprotein VI receptor diffusion, localisation and dimerisation in platelet lipid rafts

Figure 4The alt text for this image may have been generated using AI.

Higher diffusivity ratio enhances receptor confinement and dimerisation. (A) Snapshots of simulation of receptors in monomeric (red) or dimeric (orange) forms in the presence of a confined domain (yellow circle). Initially, 47 monomeric receptors were randomly distributed without dimeric form. Simulations were run for ≥ 200,000 steps, with an average of the last 50,000 steps shown. The diffusivity ratio between outside and inside confined domains, Dout:Din, was varied from 1 (20) to 1024 (210). Snapshots are shown for Dout:Din = 1, 4, 16, 64, 256 and 1024. (B) Effect of altering the ratio of Dout:Din on the number of receptors in dimeric form. Simulations were repeated three times, means ± SD.

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