Figure 6

Merging of confined domains has no effect on receptor dimerisation. Simulated was the effect of merging two confined domains while fixing the total occupied area size. (A) Snapshots of two confined domains merged into one (yellow circles). The red and orange dots represent monomeric and dimeric receptors, respectively. (B) Simulation for determining dimeric receptors as a function of the fold merging of confined domains. Simulations were repeated three times, mean ± SD; Pearson correlation of 0.40 indicates a weak positive correlation between confined domain folds and dimerisation.