Figure 7

Increasing inert protein crowding induces more receptor dimerisation. Simulation of added inert proteins on the receptor dimerisation. Red and orange dot represents monomeric and dimeric receptors, respectively; green dots represent inert proteins. Simulations were run for ≥ 100,000 steps, with an average of the last 50,000 steps shown. (A) Snapshots from the left top with inert proteins of 50, 100, 150 and 200. (B) Plot of dimer counts versus number of inert proteins. Note the more abundant dimeric receptors, when protein crowdedness increases. Each simulation was repeated three times, mean ± SD.