Figure 2 | Scientific Reports

Figure 2

From: ATP synthase interactome analysis identifies a new subunit l as a modulator of permeability transition pore in yeast

Figure 2

Mco10 and Atp19 phylogenetic and structural analysis. (a) Alignment of Mco10 and Atp19 sequences by Clustal Omega. (b) Hydropathy plots of Mco10 and Atp19 by Kate and Doolittle method using ProtScale on the ExPASy Server. (c) Structures of Mco10 and Atp19 as predicted in the model from AlphaFold2 database. The color code represents the model confidence as determined by the AI algorithm of AlphaFold2. The alignment was done using PyMol molecular visualization software. (d) AlphaFold’s expected position error PAE plot of Mco10 and Atp19. (e) Phylogenetic tree analysis of Mco10, Atp19 and related homologs in fungi. The tree was constructed using Maximum likelihood method with representative species from all subphylum of Ascomycota and representative examples of Basidiomycota. (1) represents Mco10 related homolog and (2) represents Atp19 related homolog when there were two distinct proteins present in the genome of the organism.

Back to article page