Table 1 Comparison of clinical characteristics among the three groups based on the GNRI values.
From: The Geriatric Nutritional Risk Index predicts sarcopenia in patients with cirrhosis
Variable | ALL | L-GNRI | I-GNRI | H-GNRI | p-value |
|---|---|---|---|---|---|
Patients, n (%) | 202 | 49 (24.3) | 103 (51.0) | 50 (24.8) | |
Men, n (%) | 132 (65.3) | 30 (61.2) | 66 (64.1) | 36 (72.0) | 0.492 |
Age (years) | 69.0 (59.0–76.0) | 70.0 (59.0–76.5) | 71.0 (63.0–76.0) | 64.0 (53.0–73.0) | 0.021 |
BMI (kg/m2) | 23.6 (21.2–26.1) | 20.6 (19.0–22.2) | 23.2 (21.5–25.1) | 27.8 (25.4–30.3) | < 0.001 |
Etiology | |||||
HBV/HCV/Alcohol/other, n | 18/67/64/53 | 0/18/17/14 | 13/33/33/24 | 5/16/14/15 | 0.290 |
Child–Pugh score | 6 (5–7) | 7 (6–8) | 5 (5–7) | 5 (5–5) | < 0.001 |
Child–Pugh A/B + C, n | 138/64 | 16/33 | 74/29 | 48/2 | < 0.001 |
ALBI score | − 2.53 (− 2.85– − 2.05) | − 1.85 (− 2.14– − 1.65) | − 2.56 (− 2.85– − 2.18) | − 2.85 (− 3.01– − 2.58) | < 0.001 |
mALBI grade (1/2a/2b/3) | 90/40/68/4 | 5/3/37/4 | 48/25/30/0 | 37/12/1/0 | < 0.001 |
GNRI | 102.6 (94.0–109.5) | 87.6 (80.8–91.1) | 102.5 (97.6–106.2) | 115.7 (111.0–120.7) | < 0.001 |
Total bilirubin (mg/dL) | 0.9 (0.6–1.3) | 1.0 (0.5–1.6) | 0.9 (0.6–1.3) | 0.9 (0.7–1.1) | 0.966 |
Albumin (g/dL) | 3.9 (3.4–4.2) | 3.2 (2.8–3.5) | 3.9 (3.6–4.2) | 4.4 (4.0–4.5) | < 0.001 |
Prothrombin time (%) | 82 (68–94) | 78 (60–93) | 82 (67–96) | 85 (74–93) | 0.163 |
eGFR (mL/min/1.73 m2) | 64 (51–77) | 65 (42–79) | 65 (51–77) | 61 (51–77) | 0.999 |
M2BPGi (C.O.I) | 3.06 (1.54–6.16) | 5.64 (2.83–8.07) | 2.99 (1.66–5.79) | 1.66 (1.10–3.41) | < 0.001 |
BCAA (µmol/L) | 398 (325–477) | 340 (300–395) | 402 (326–461) | 463 (393–505) | < 0.001 |
Zinc (µg/dL) | 63 (54–74) | 54 (43–64) | 64 (55–73) | 73 (61–85) | < 0.001 |
Handgrip strength (kg) | |||||
All patients | 25.3 (18.5–34.9) | 21.5 (16.6–28.8) | 25.3 (19.1–34.0) | 31.5 (22.5–41.0) | < 0.001 |
Men | 31.6 (25.0–37.4) | 25.6 (20.5–33.0) | 31.6 (25.2–36.7) | 37.8 (28.9–43.5) | < 0.001 |
Women | 17.2 (14.4–22.3) | 16.8 (14.6–20.0) | 17.9 (14.5–22.5) | 21.9 (12.9–23.2) | 0.456 |
SMI (kg/m2) | |||||
All patients | 6.92 (5.95–7.85) | 6.37 (5.36–6.94) | 6.81 (5.96–7.63) | 7.93 (6.95–8.73) | < 0.001 |
Men | 7.34 (6.78–8.23) | 6.82 (6.32–7.11) | 7.33 (6.71–8.02) | 8.22 (7.39–9.00) | < 0.001 |
Women | 5.83 (5.20–6.39) | 5.53 (5.05–6.11) | 5.84 (5.08–6.34) | 6.43 (5.80–7.46) | 0.011 |
Sarcopenia, n (%) | 56 (27.7) | 24 (49.0) | 28 (27.2) | 4 (8.0) | < 0.001 |
Gait speed (m/s) | 1.06 (0.85–1.25) | 1.04 (0.75–1.21) | 1.06 (0.86–1.21) | 1.12 (0.99–1.35) | 0.045 |
Slow gait speed, n (%) | 73 (36.1) | 22 (44.9) | 38 (36.9) | 13 (26.0) | 0.144 |
