Table 3 Levels of the inflammatory cytokines IL-4, IL-13 and IL-33 in MPN subgroups regardless of signs of AMD and comparisons between groups.

From: Serum levels of IL-4, IL-13 and IL-33 in patients with age-related macular degeneration and myeloproliferative neoplasms

Inflammatory cytokines (serum)

ET (n = 17)

PV (n = 39)

PMF (n = 6)

p value ET versus PV

p-value PV versus PMF

p value ET versus PMF

IL-4 pg/mL, median (IQR)

0.30 (0.28–0.32)

0.31 (0.28–0.34)

0.29 (0.29–0.33)

0.305

0.708

0.865

IL-13 pg/mL, median (IQR)

1.22 (0.93–1.72)

1.45 (0.85–2.71)

1.20 (0.98–1.41)

0.9

0.61

0.871

IL-33 pg/mL, median (IQR)

1.28 (1.25–1.42)

1.30 (1.24–1.44)

1.36 (1.29–1.39)

0.958

0.757

0.973

  1. IL interleukins, IQR interquartile range, ET essential thrombocythemia, PV polycythemia vera, PMF primary myelofibrosis.
  2. Statistical comparisons between groups:
  3. aWiloxons rank-sum test.
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