Figure 2 | Scientific Reports

Figure 2

From: Inhibition of NHE1 transport activity and gene transcription in DRG neurons in oxaliplatin-induced painful peripheral neurotoxicity

Figure 2

Effect of OHP on resting pHi and NHE1 activity. pHi recovery from an acid load in three untreated DRG neurons (a) and in neurons incubated for 1 h with 0.1 μg/ml of OHP (b). Panels (c) and (d) represent the instantaneous pHi rate of change versus time of traces in (a) and (b), which were used to compute the pHi dependence of the total acid extrusion J (e, f). Statistical plots (Mann–Whitney U test) compare control (black) and OHP-treated (red) resting pHi (g) and the maximum rate of recovery dpH/dtMAX (h).

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