Figure 3 | Scientific Reports

Figure 3

From: Inhibition of NHE1 transport activity and gene transcription in DRG neurons in oxaliplatin-induced painful peripheral neurotoxicity

Figure 3

Effect of 5-FU and FK506 on steady state pHi and NHE1 activity. Three exemplary traces of pHi recovery from an acid load in DRG neurons incubated with: VEH (a), 5-FU (b), CAR (c), FK506 (d), FK506 and OHP (e). Statistical plots (Kruskal–Wallis and Dunn’s test) comparing resting pHi (f) and the maximum rate of recovery dpH/dtMAX (g) values obtained in the five experimental conditions.

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