Table 1 Participant demographics: PTSD and HC.

From: Investigating TSPO levels in occupation-related posttraumatic stress disorder

 

PTSD (n = 17)

HC (n = 22)

p value

Age, years

44 ± 10.1

34.6 ± 13.9

0.01A

Sex, male n (%)

8 (47)

11 (47)

0.829C

NIH race, Caucasian n (%)

13 (76)

12 (52)

0.591C

BMI (kg/m2)

26.5 ± 4

24.8 ± 4.1

0.195A

TSPO genotype, HAB n (%)

8 (47)

12 (54)

0.678C

Years of education

15.6 ± 2.9

15.5 ± 2

0.912A

Cigarette smokers, n (%)

3 (17) (4 former smokers)

1 (4) (2 former smokers)

0.651C

Positive THC on PET day, n (%)

7 (41)

4 (23)

0.123C

Current Cannabis use, n (%)

6 (35) [3 daily]

7 (30)

0.914C

Cannabis (g/week)

17.9 ± 30.2

2.3 ± 2.1

0.377A

Alcohol (drinks/week)

2.71 ± 2.4

2.69 ± 1.9

0.959A

Questionnaires

 BDI, median (range)

21.7 (4–39)+

2.4 (1–4.5)+

< 0.001A

 GAD-7, median (range)

9.3 (0–21)*

0 (0–2.5)*

< 0.001A

 PHQ-9, median (range)

12.3(1–27)*

3 (0.5–3)*

< 0.001A

Scan parameters, mean (range)

 Amount injected (mCi)

4.9 (4.49–5.29)

5.1 (4.63–6.62)

0.02B

 Specific activity at time of injection (mCi/μmol)

4575 (1053–9395)

3188 (1047–7825)

0.134B

 Mass injected (μg)

0.91 (0.23–2.53)

0.58 (0.13–1.7)

0.06B

  1. Values are mean ± SD unless otherwise indicated.
  2. Evaluated by T-TestA , Mann–Whitney U TestB, Chi Square TestC.
  3. PTSD: n = 10* & n = 20 + .
  4. HC: n = 15* & n = 14 + .
  5. BMI Body mass index, HAB high affinity binder, BDI Beck Depression Inventory, GAD-7 General Anxiety Disorder-7, g grams, NIH National Institute of Health, PHQ-9 Patient Health Questionnaire-9, THC tetrahydrocannabinol, TSPO translocator protein.
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