Table 1 Characteristics of the KORA F3 study (n = 3,071).

From: A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study

Variable

Age (in years)

57.4 ± 12.88 [46.0, 57.0, 67.0]

Women

1575 (51.2%)

Anthropometric measurements

Weight (in kg)

77.93 ± 15.00 [66.90,76.80,87.60]

BMI

27.66 ± 4.61 [24.42, 27.13, 30.28]

Height (in cm)

167.7 ± 9.46 [160.5, 167.4, 174.6]

Waist circumference (in cm)

94.93 ± 13.15 [85.6, 95.10, 103.60]

Hip circumference (in cm)

106.9 ± 8.98 [100.9, 105.6, 111.8]

Waist-Hip-Ratio

0.8867 ± 0.085 [0.8240, 0.8890, 0.9470]

Lifestyle

Physically active

1589 (51.7%)

Categorizations of physical activity

 

  Regularly > 2 h per week

688 (22.4%)

  Regularly active for ~ 1 h per week

901 (29.3%)

  Irregularly active for ~ 1 h per week

460 (15%)

  Little to no physical activity

1,022 (33.3%)

Smoking categories

  Regular smoker

490 (16.0%)

  Irregular smoker

52 (1.7%)

  Ex-smoker

1078 (35.1%)

  Never-smoker

1283 (41.8%)

Family history for diabetes

T2D in any parent

777 (25.5%)

Categorization of Family Risk score FamRS

  Average

2582 (84.7%)

  Positive FamRS

343 (11.2%)

  Strong positive FamRS

125 (4.1%)

Blood values

 Glucose (mg/dl)

107.2 ± 32.27 [91.0, 100.0, 113.0]

 HbA1c-values (%)

5.369 ± 0.54 [5.100, 5.300, 5.500]

 Total cholesterol (mg/dl)

218.3 ± 39.94 [191.0, 216.0, 243.0]

 HDL cholesterol (mg/dl)

58.77 ± 17.15 [46.00, 56.00, 69.00]

 LDL cholesterol (mg/dl)

128 ± 32.63 [105, 127, 148]

 Triglycerides (mg/dl)

165.2 ± 126.05 [88.0, 136.0, 201.0]

Diabetes

Number of prevalent Type 2 cases, n (%)

256 (8.3%)

Number of incident Type 2 cases, n (%)

163 (5.3%)

  1. Continuous variables are shown as mean ± SD and [25%, 50%, 75%] percentile; Categorical variable in n (%).