Figure 2
P-gp protein expression and maternal BMI in placental tissue. (A) P-gp protein expression in the three maternal BMI groups; normal weight (BMI: 18.5–24.9 kg/m2 (n = 14)), overweight (BMI: 25–29.9 kg/m2 (n = 10)), and obese (BMI ≥ 30 kg/m2 (n = 14)). No statistically significant difference was found (one-way ANOVA, F(2,35) = 1.080, p = 0.351). A p value < 0.05 was considered statistically significant. Each bar represents mean ± SD. (B) Protein expression of P-gp analyzed by linear regression. Each dot represents one sample (n = 38), and line represents best fitted line. Slope = 0.039, F(1,36) = 2.59, R2 = 0.067, p = 0.116. A p value < 0.05 was considered statistically significant. (C) Western blot of P-gp and loading control CYPB, cropped blots. Full blots available in Supplementary Fig. S3–S4.
