Table 3 Relation between the studied miRNAs and hematological characteristics of DLBCL patients.

From: Lymphocyte to monocyte ratio predicts survival and is epigenetically linked to miR-222-3p and miR-26b-5p in diffuse large B cell lymphoma

Characteristics

Mir-222-3p

P value

Mir-26b-5p

P value

ebv-miR-BHRF1-5p

P value

ebv-miR-BHRF1-2-3p

P Value

 ≤ −2

 ≥ 2

 ≤ -2

 ≥ 2

 ≤ -2

− 1.9–1.9

 ≥ 2

 ≤ −2

 ≥ 2

Lym/mon

  < 3

2 (11.1%)

14 (77.8%)

0.043 (corrected 0.559)

2 (11.1%)

16 (88.9%)

0.043* (corrected 0.559)

1 (5.6%)

3 (16.7%)

14 (77.8%)

0.202

7 (38.9%)

11 (61.1%)

0.200

  ≥ 3

8 (40.0%)

15 (68.2%)

8 (40.0%)

12 (60.0%)

4 (20.0%)

6 (30.0%)

10 (50.0%)

4 (20.0%)

16 (80.0%)

Neut/mon

  < 8

4 (18.2%)

18 (81.8%)

0.142

4 (18.2%)

18 (81.8%)

0.142

3 (13.6%)

3 (13.6%)

16 (72.7%)

0.235

7 (31.8%)

15 (68.2%)

0.736

  ≥ 8

6 (40.0%)

9 (60.0%)

6 (40.0%)

9 (60.0%)

2 (13.3%)

6 (40.0%)

7 (46.7%)

4 (26.7%)

11 (73.3%)

Pl/lym

  < 134

6 (30%)

14 (70%)

0.625

6 (30%)

14 (70%)

0.625

6 (31.6%)

3 (15.8%)

10 (52.6%)

0.241

12 (63.2%)

7 (36.8%)

0.812

  ≥ 134

3 (17.6%)

14 (82.4%)

3 (17.7%)

14 (82.3%)

2 (11.1%)

2 (11.1%)

14 (77.8%)

13 (72.3%)

5 (27.7%)

Neu/lym

  < 2.131

7 (35%)

13 (65%)

0.177

5 (25%)

15 (75%)

0.861

5 (26.3%)

3 (15.8%)

11 (57.9%)

0.787

14 (73.7%)

5 (26.3%)

0.727

 ≥ 2.131

2 (11.1%)

16 (88.9%)

5 (27.8%)

13 (72.2%)

4 (21.1%)

2 (10.5%)

13 (68.4%)

12 (63.2%)

7 (36.8%)

SII

  < 477.189

6 (31.6%)

13 (68.4%)

0.712

6 (30%)

14 (70%)

0.861

4 (21.1%)

2 (10.5%)

13 (68.4%)

0.106

6 (31.6%)

13 (68.4%)

0.727

  ≥ 477.189

4 (21.1%)

15 (78.9%)

4 (22.2%)

14 (77.8%)

2 (10.5%)

2 (10.5%)

15 (79%)

6 (31.6%)

13 (68.4%)

Hb

  < 12

6 (28.6%)

15 (71.4%)

0.726

6 (28.6%)

15 (71.4%)

0.726

3 (14.3%)

6 (28.6%)

12 (57.1%)

0.719

3 (14.3%)

18 (85.7%)

0.027* (corrected p = 0.648)

  ≥ 12

4 (23.5%)

13 (76.5%)

4 (23.5%)

13 (76.5%)

2 (11.8%)

3 (17.6%)

12 (70.6%)

8 (47.1%)

9 (52.9%)

PLT

  < 150

1 (14.3%)

6 (85.7%)

0.424

1 (14.3%)

6 (85.7%)

0.424

0 (0.0%)

2 (28.6%)

5 (71.4%)

0.697

3 (42.9%)

4 (57.1%)

0.390

  ≥ 150

9 (29.0%)

22 (71.0%)

9 (29.0%)

22 (71.0%)

5 (16.1%)

7 (22.6%)

19 (61.3%)

8 (25.8%)

23 (74.2%)

  1. Diffuse Large B Cell Lymphoma (DLBCL), Lymphocyte/Monocyte ratio (Lym/mon), Neutrophil monocyte ration (Neut/mon), Platelet lymphocyte ratio (Pl/lym), Neutrophil lymphocyte ration (Neu/lym), Systemic immune-inflammation index (SII), Hemoglobin (Hb), Platelets (PLT), Significant (0.043*).
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