Table 3 Body weight, serum glucose level, lipid profile, liver and kidney functions in control and obese groups without ZnSO4 tretatment, low dose (15 mg) ZnSO4 treatment, and high dose (30 mg) ZnSO4 treatment in male rats.

From: Ameliorative effects of zinc supplementation on cognitive function and hippocampal leptin signaling pathway in obese male and female rats

Studied parameters

Control group

Obese group

Without ZnSO4

Low dose ZnSO4

High dose ZnSO4

Without ZnSO4

Low dose ZnSO4

High dose ZnSO4

Body weight (g)

313.4 ± 22.8bc

300.6 ± 6.4bc

289.4 ± 24.9c

419.0 ± 8.2a

324.3 ± 42.7b

303.9 ± 20.4b

Glucose (mg/dl)

92.7 ± 10.7cd

93.7 ± 7.7bcd

91.0 ± 6.6cd

130.3 ± 3.5a

94.2 ± 6.6bcd

96.7 ± 9.8bc

Lipid profile

 Lipids (mg/dl)

347.4 ± 19.1b

347.9 ± 21.8b

323.5 ± 25.4bc

406.5 ± 22.6a

355.7 ± 14.4b

343.3 ± 16..2bc

 Cholesterol (mg/dl)

97.0 ± 7.3bc

97.7 ± 14.2bc

99.0 ± 26.8bc

129.0 ± 10.3a

111.0 ± 28.0ab

112.3 ± 13.6ab

 Triglyceride (mg/dl)

94.7 ± 10.4c

90.0 ± 18.2c

90.7 ± 15.0c

196.3 ± 17.3a

157.3 ± 7.4b

153.3 ± 12.0b

Liver enzymes

 GOT (U/L)

167.3 ± 13.2bcd

162.2 ± 13.6cde

131.4 ± 13.0ef

275.0 ± 57.1a

199.2 ± 27.7b

173.0 ± 10.7bc

 GPT (U/L)

63.1 ± 4.1b

48.9 ± 7.6cd

47.0 ± 8.9cde

93.1 ± 5.0a

40.9 ± 5.4ef

41.1 ± 5.8def

Kidney functions

 Urea (mg/dl)

34.0 ± 2.0e

37.3 ± 3.0bcde

37.0 ± 4.3cde

42.2 ± 2.6a

38.3 ± 1.9abcd

38.4 ± 2.1abc

 Uric acid (mg/dl)

2.6 ± 0.4e

3.0 ± 0.4de

3.3 ± 0.5cde

2.6 ± 0.4e

3.3 ± 0.6cde

3.4 ± 0.2cd

 Creatinine (mg/dl)

0.6 ± 0.07ab

0.7 ± 0.07a

0.6 ± 0.06ab

0.6 ± 0.05ab

0.6 ± 0.07ab

0.6 ± 0.08ab

  1. Data was expressed using mean ± SD.
  2. Means in the same raw with small common letters are not significant (i.e. means with different letters are significant).
  3. SD standard deviation.