Figure 2
From: Coenzyme A binding sites induce proximal acylation across protein families
Lysine acylation is significantly over-represented on CoA-binding proteins. (a) Diagram of acetylation, succinylation, glutarylation modifications to protein lysine residues. (b) Table showing the enrichment of acetylated lysines on CoA-binding proteins analyzed in a whole-cell mouse liver acetylome dataset. This enrichment is also present when the dataset was separated into non-mitochondrial and mitochondria lysines. Significance was calculated using Fisher’s exact test. (c) Table showing the enrichment of acetylated, succinylated, and glutarylated lysines on CoA-binding proteins, using mitochondrial mouse liver datasets. For (b) and (c), statistical significances were calculated using Fisher’s exact test.
