Table 2 List of enriched variant pathways shared by “multilesional” and “unilesional” patients diagnosed with Pyoderma gangrenosum.

From: Different molecular pathways are disrupted in Pyoderma gangrenosum patients and are associated with the severity of the disease

Reactome ID

Pathway name

R-HSA-189483

Heme degradation

R-HSA-2995410

Nuclear Envelope (NE) Reassembly

R-HSA-418457

cGMP effects

R-HSA-450302

Activated TAK1 mediates p38 MAPK activation

R-HSA-5210891

Uptake and function of anthrax toxins

R-HSA-8876725

Protein methylation

R-HSA-8941284

RUNX2 regulates chondrocyte maturation

R-HSA-983695

Antigen activates B Cell Receptor (BCR) leading to generation of second messengers

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