Figure 2 | Scientific Reports

Figure 2

From: MRI-based long-term follow-up of indolent orbital lymphomas after curative radiotherapy: imaging remission criteria and volumetric regression kinetics

Figure 2

Volumetric data of orbital lymphomas prior to irradiation (T0); < 6 months (T1), 6–12 months (T2), 12–24 months (T3), 24–36 months (T4) 36–48 months (T5) and > 48 months (T6) after treatment. (A) The absolute tumor volume sharply decreases after treatment. (B) Exponential model with two components and final offset. The relative lesion volume was normalized to the pre-treatment volume. The x-axis shows the time after the last treatment fraction in days. The fast decay already occurs before the first follow-up MRI. The slow component accounts for 22.8% (95% confidence interval 16.9–28.7%) of the decay. It has a half time of 139.2 days (95% confidence interval 87.6–338.1 days). (C) The median, absolute lesion diameter quickly falls below 1 cm. (D) Kaplan–Meier plot showing the progression free survival rates of patients that achieved a complete response (dotted line) versus patients with persisting tumor residue after treatment (non-CR group, solid line). The differences were not statistically significant (Log Rank test, p = 0.915).

Back to article page