Figure 1 | Scientific Reports

Figure 1

From: Scar/WAVE has Rac GTPase-independent functions during cell wound repair

Figure 1

SCAR is recruited to cell wounds faster than Rac1 or Rac2. Confocal projection images of embryos expressing an actin reporter (sGMCA; A-A’) or co-expressing mCherry-Rac1 and sGMCA (B), GFP-Rac2 and sStMCA (C), and GFP-SCAR and sStMCA (D). Times post-wounding are indicated. UW = unwounded. Arrows indicate recruitment to the wound periphery. (E–G) Fluorescence intensity (arbitrary units) profiles across the wound area over time for the images shown in (B–D), respectively. (H) Dotplot of initial actin, Rac1, Rac2, and SCAR recruitment to wounds. Scale bars: 20 μm.

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