Figure 6

Examination of progenitor, and pluripotent gene expression. Bar graphs show log₂Fold change (Log₂FC) in selective gene expression for each CD29⁺/CD44⁺ cell sample as compared to undifferentiated stem cells (A/C) or as compared to the D10 isolated cells (B). Genes analysed comprise those associated with (A/B) neurogenic and progenitor factors and (C) pluripotent stem cell markers. We regarded a 1.32 log2 fold change (increase and decrease) the cut off for significant change in expression (corresponds to fold changes of 2.5 and 0.4). Legend shows the age of the organoid to which the CD29⁺/CD44⁺ cells were isolated.