Table 1 Performance of the classifier A (shallow neural network in the case of 3D RI tomograms and logistic regression in the case of 2D QPMs) and the classifier B (shallow neural network in the case of 3D RI tomograms and linear discriminant in the case of 2D QPMs) over the test set.

From: Label-free liquid biopsy through the identification of tumor cells by machine learning-powered tomographic phase imaging flow cytometry

Metric

Classifier A

Classifier B

3D RI tomogram

2D QPM

3D RI tomogram

2D QPM

MC

Tumor cell

NB

OC

NB

OC

MC

Tumor cell

Accuracy

97.4

87.3

97.3

85.2

True positive rate (sensitivity or recall)

95.7

97.8

96.7

98.3

82.8

90.0

63.8

93.4

True negative rate (specificity)

97.8

95.7

98.3

96.7

90.0

82.8

93.4

63.8

Positive predictive value (precision)

91.8

98.9

99.2

93.7

94.4

72.0

71.4

90.9

Negative predictive value

98.9

91.8

93.7

99.2

72.0

94.4

90.9

71.4

Balanced accuracy

96.8

78.6

97.5

86.4

F1 score

93.8

98.3

97.9

95.9

88.2

86.4

67.4

92.1

Matthews correlation coefficient

92.1

59.7

93.9

69.5

Fowlkes–Mallows index

93.8

98.3

97.9

96.0

88.4

80.5

67.5

92.1