Figure 3

Timeline of the acquisitions and changes of Stx1a phages throughout the evolution of ST21. The estimated timing of acquisitions and changes to Stx1a phages are indicated by coloured triangles in a maximum clade credibility tree of ST21 strains. Tips, branches and internal nodes in C1_sc3.2, C1_sc3.4, and C2 are brought together under open triangles. A C2 strain (DB02) lacking temporal information was not included in this tree. The complete topology of the tree is shown in Supplementary Figure S4.