Table 3 Significant genes from the the 2 h timepoint. atxA did not experience a significant fold-change however the FDR did make the cutoff. Bolded entries indicate the gene is present on the virulence plasmid pXO1. Gene loci are listed according to NCBI Sterne RefSeq assembly GCF_000832635.1 (Locus AW20) with the RefSeq assembly GCF_000008165.1 loci provided (Locus BAS) where available. Protein name and functions are according to PATRIC and the log2FC are shown.
Locus (AW20) | Locus (BAS) | Protein id | log2FC |
|---|---|---|---|
AW20_4874 | BAS3350 | Hypothetical protein; YfhD-like sporulation-specific sigma-F regulated | 116.33 |
AW20_5643 | Hypothetical protein; nuclease domain protein downstream of lef, pXO1 | 32.20 | |
AW20_1990 | Hypothetical protein | 15.27 | |
AW20_5714 | Hypothetical protein, pXO1 | 14.91 | |
AW20_21 | Acetyltransferase, GNAT family | 14.33 | |
AW20_3821 | BAS4374 | FIG016877: hypothetical protein | 11.80 |
AW20_4418 | BAS3801 | Prophage pi2 protein 35 | 7.59 |
AW20_3318 | BAS4843 | Uncharacterized DUF1805-containing protein YunC | 7.23 |
AW20_705 | BAS1952 | Hypothetical protein | 6.84 |
AW20_4729 | BAS3492 | Hypothetical protein; prophage LambdaBa01, transcriptional regulator, AbrB family | 6.56 |
AW20_5607 | Hypothetical protein, pXO1 | 5.66 | |
AW20_1773 | BAS0913 | Hypothetical protein | 5.32 |
AW20_286 | BAS2363 | Hypothetical protein, GBAA2540 homolog | 4.18 |
AW20_4403 | BAS3814 | Hypothetical protein | 3.79 |
AW20_1378 | BAS1298 | Hypothetical protein, regulatory YrvL family protein | 3.00 |
AW20_3164 | BAS4995 | Stage V sporulation protein AC (SpoVAC) | 2.80 |
AW20_2179 | BAS0537 | Glycerol-3-phosphate ABC transporter, permease protein UgpE | 2.35 |
AW20_1941 | BAS0749 | Uncharacterized MFS-type transporter | 2.26 |
AW20_1364 | BAS1310 | Ketol-acid reductoisomerase (NADP( +)) | 2.11 |
AW20_981 | BAS1681 | MutT/Nudix family protein | 2.00 |
AW20_170 | BAS2472 | EDD, DegV family protein | 1.93 |
AW20_4951 | BAS3273 | Hypothetical protein | 1.88 |
AW20_2438 | BAS0315 | Polysaccharide deacetylase | 1.82 |
AW20_917 | BAS1745 | Hypothetical protein | 1.74 |
AW20_5718 | Hypothetical protein, pXO1 | 1.70 | |
AW20_3836 | BAS4360 | Uroporphyrinogen-III synthase | 1.62 |
AW20_5499 | BAS2739 | Hypothetical protein | 1.60 |
AW20_5054 | BAS3171 | ATP synthase protein I | 1.59 |
AW20_163 | BAS2480 | Hypothetical protein | 1.58 |
AW20_2395 | BAS0356 | Methyl-accepting chemotaxis protein | 1.52 |
AW20_4704 | BAS3516 | Hypothetical protein | 1.47 |
AW20_330 | BAS2320 | Hypothetical protein | 1.46 |
AW20_2243 | BAS0493 | Small acid-soluble spore protein, gamma-type SASP | 1.38 |
AW20_3302 | BAS4859 | Glycine cleavage system H protein | 1.38 |
AW20_720 | BAS1937 | Uncharacterized membrane protein Bsu0528 (YdeO) | 1.29 |
AW20_4754 | BAS3468 | UPF0154 protein YneF | 1.24 |
AW20_1933 | BAS0757 | Enterotoxin / cell-wall binding protein | 1.23 |
AW20_1605 | BAS1076 | Catalase KatE | 1.22 |
AW20_944 | BAS1718 | Threonine dehydratase biosynthetic | 1.21 |
AW20_1190 | BAS1482 | Uncharacterized protein YpbS | 1.21 |
AW20_594 | BAS2061 | Hydrolase, alpha/beta fold family | 1.20 |
AW20_2908 | BAS5250 | Uracil-DNA glycosylase, family 1 | 1.18 |
AW20_1379 | BAS1297 | Uncharacterized protein SAV1929 | 1.13 |
AW20_2124 | BAS0590 | Nitric oxide reductase activation protein NorD | 1.09 |
AW20_2878 | BAS5280 | Glycosyl transferase, group 2 family | 1.07 |
AW20_2879 | BAS5279 | Membrane protein exporting O-antigen, teichoic acid lipoteichoic acids | 1.05 |
AW20_3899 | BAS4296 | HesA/MoeB/ThiF family protein | 1.04 |
AW20_877 | BAS1784 | L-lactate dehydrogenase | 1.04 |
AW20_4199 | BAS4003 | Acetyltransferase, GNAT family | 1.02 |
AW20_2510 | BAS0254 | GMP synthase [glutamine-hydrolyzing], amidotransferase subunit | 1.02 |
AW20_2971 | BAS5187 | CTP synthase | 1.01 |
AW20_918 | BAS1744 | Rhodanese domain protein UPF0176, Firmicutes subgroup | 1.00 |
AW20_1906 | BAS0785 | Outer surface protein of unknown function, cellobiose operon | − 1.00 |
AW20_5111 | BAS3116 | Uncharacterized membrane protein YwiC | − 1.01 |
AW20_4184 | Hypothetical protein | − 1.03 | |
AW20_983 | BAS1679 | Uncharacterized protein YndH | − 1.06 |
AW20_5555 | BAS2692 | Integral membrane protein; YeaQ/YmgE family | − 1.06 |
AW20_728 | BAS1929 | Phosphoglycerate mutase family 3 | − 1.06 |
AW20_1125 | BAS1547 | Chemotaxis protein methyltransferase CheR | − 1.11 |
AW20_1033 | BAS1630 | Transcriptional regulator, GntR family | − 1.12 |
AW20_4348 | BAS3861 | UPF0358 protein YlaN | − 1.12 |
AW20_4085 | BAS4114 | Transcriptional regulator, AcrR family | − 1.13 |
AW20_5770 | Hypothetical protein, pXO1 | − 1.16 | |
AW20_4157 | BAS4044 | Probable metallo-hydrolase YqjP | − 1.17 |
AW20_3880 | BAS4316 | Holliday junction ATP-dependent DNA helicase RuvA | − 1.18 |
AW20_408 | BAS2248 | Acetyltransferase, GNAT family | − 1.19 |
AW20_1384 | BAS1293 | Transcriptional regulator, Bla/Mec family | − 1.19 |
AW20_2259 | BAS0480 | Glycosyl transferase, group 2 family | − 1.19 |
AW20_2489 | BAS0269 | Undecaprenyl-diphosphatase (EC 3.6.1.27) | − 1.19 |
AW20_1586 | BAS1095 | 3-oxoacyl-[acyl-carrier-protein] synthase, KASIII (EC 2.3.1.180) | − 1.20 |
AW20_3574 | BAS4612 | Glucose 1-dehydrogenase (EC 1.1.1.47) | − 1.21 |
AW20_125 | BAS2516 | GNAT family acetyltransferase BA2701 | − 1.21 |
AW20_3613 | BAS4574 | Hypothetical protein | − 1.22 |
AW20_4494 | BAS3724 | UPF0701 protein YicC | − 1.23 |
AW20_4337 | BAS3872 | DUF1054 superfamily protein | − 1.23 |
AW20_5265 | BAS2966 | Manganese ABC transporter, ATP-binding protein SitB | − 1.27 |
AW20_4091 | BAS4108 | Mn-dependent transcriptional regulator MntR | − 1.29 |
AW20_5476 | BAS2761 | Hypothetical protein | − 1.43 |
AW20_3618 | BAS4568 | Virulence factor MviM | − 1.44 |
AW20_1154 | BAS1518 | Putative cation/acetate symporter | − 1.44 |
AW20_5667 | Hypothetical protein; cytolysin domain upstream from cya, pXO1 | − 1.45 | |
AW20_3928 | BAS4267 | Acetaldehyde/alcohol dehydrogenase | − 1.46 |
AW20_3102 | BAS5058 | PTS system, cellobiose-specific IIC component | − 1.49 |
AW20_1735 | BAS0950 | Putative ring-cleaving dioxygenase MhqA | − 1.51 |
AW20_4872 | BAS3352 | Uncharacterized membrane protein YuiD | -1.60 |
AW20_1801 | BAS0887 | Transcriptional regulator, TetR family | − 1.67 |
AW20_4647 | BAS3570 | Gamma-aminobutyrate (GABA) permease | − 2.38 |
AW20_4254 | BAS3950 | Hypothetical protein | − 2.59 |
AW20_5232 | BAS2997 | Hypothetical protein | − 2.75 |
AW20_2269 | BAS0470 | Hypothetical protein | − 2.85 |
AW20_360 | BAS2292 | Hypothetical protein | − 3.47 |
AW20_817 | BAS1844 | Small acid-soluble spore protein, alpha/beta family, SASP_1 | − 5.79 |
AW20_1924 | BAS0767 | Polypeptide composition of the spore coat protein CotJB | − 6.18 |
AW20_5645 | Hypothetical protein DUF4037, between lef and pagR, pXO1 | − 7.07 | |
AW20_1760 | BAS0925 | Hypothetical protein | − 8.30 |
AW20_5242 | Hypothetical protein | − 8.42 | |
AW20_4375 | Hypothetical protein | − 151.92 | |
AW20_5658 | Transcriptional activator AtxA, (pXO1-119) | − 0.62 |
