Table 3 A comparison between group A and group B.

From: Outer nuclear layer recovery as a predictor of visual prognosis in type 1 choroidal neovascularization of neovascular age-related macular degeneration

 

Group A (n = 46)

Group B (n = 48)

P value

ONL change (µm)‡

− 1.3 ± 8.9

+ 21.5 ± 9.0

< 0.001*

Number of injections

7.3 ± 3.8

6.9 ± 3.7

0.621*

Duration of symptom (days)

36.5 ± 42.8

34.5 ± 93.6

0.903*

PVD status (with/without)

20/23

18/18

0.823

BCVA (logMAR)

 Baseline

0.51 ± 0.24

0.45 ± 0.31

0.250*

 After 3 loading doses

0.41 ± 0.24

0.27 ± 0.25

0.010*

 At 1-year

0.43 ± 0.27

0.22 ± 0.19

< 0.001*

ONL thickness (μm)

 Baseline

53.0 ± 22.7

56.3 ± 15.9

0.404*

 After 3 loading doses

51.6 ± 21.8

77.9 ± 18.1

< 0.001*

 At 1-year

56.7 ± 26.8

69.6 ± 20.0

0.010*

SRF height (μm)

 Baseline

165.6 ± 84.0

178.2 ± 110.7

0.350*

 After 3 loading doses

37.3 ± 44.8

19.0 ± 38.9

0.046*

 At 1-year

64.1 ± 89.9

49.8 ± 65.9

0.377*

CNV location

  

0.012†

 Subfovea

35 (76.0%)

23 (45.5%)

 

 Juxtafovea (< 1 mm diameter circle)

10 (20.0%)

20 (45.5%)

 

 Parafovea (> 1 mm diameter circle)

1 (4.0%)

5 (9.0%)

 
  1. ONL outer nuclear layer, SRF subretinal fluid, CNV choroidal neovascularization, BCVA best-corrected visual acuity, logMAR log of minimum angle of resolution.
  2. *P values were calculated using the Student’s t test.
  3. P value was calculated using the Fisher’s exact test.
  4. ONL change between the baseline and after 3 initial loading doses.