Table 2 Clinico-demographic profile of patients based on the severity of COVID-19.

From: Clinical courses of 24,563 hospitalized COVID-19 patients during the first 12 months of the pandemic in the Central City of Iran

Variables

Total

Non sever

Sever

P-value

Age

 < 65 yr

13,139(67.2)

12,064(70.9)

1075(42.1)

 

 ≤ 65 yr

6422(32.8)

4941(29.1)

1481(57.9)

*< 0.001

Sex

 Male

10,291(52.6)

8893(52.3)

1398(54.6)

 

 Female

9285(47.4)

8124(47.7)

1161(45.4)

*0.025

 Covid-19 History(yes)

7514(38.4)

6407(1.1)

1107(2.5)

*< 0.001

 Exposure with a covid-19 patient (yes)

165(1.3)

115(37.7)

50(43.3)

*< 0.001

 Hospitalization length(days)

4.87 ± 6.64

4.5 ± 6.09

7.33 ± 9.14

*< 0.001

Breath rate

 14–18

5249(46.9)

4576(48.2)

673(39.7)

 

 18–22

4753(42.5)

4046(42.6)

707(41.7)

 

 22–28

996(8.9)

773(8.1)

223(13.1)

 

 ≥ 28

189(1.7)

95(1)

94(5.5)

*< 0.001

 Mean temperature-°C

37.11 ± 0.74

37.1 ± 0.73

37.2 ± 0.8

*< 0.001

Symptoms number. (%)

 Fever

7785(39.8)

6876(40.4)

909(30.5)

*< 0.001

 Cough

8984(45.9)

8044(47.3)

940(36.7)

*< 0.001

 Dyspnea

8349(42.6)

6618(38.9)

1731(67.6)

*< 0.001

 Chest pain

943(5.1)

840(5.3)

103(4.1)

0.012*

 Stomach ache

687(3.7)

684(4)

39(1.6)

< 0.001

 Nausea

352(1.8)

326(1.9)

26(1)

*0.001

 Vomiting

1007(5.4)

894(5.6)

113(4.5)

*0.026

 Diarrhea

682(3.7)

630(3.9)

52(2.1)

*< 0.001

 Loss of appetite

2042(11)

1731(10.8)

311(12.4)

*0.019

 Muscular. Pain

5865(30)

5296(31.1)

569(22.2)

*< 0.001

 Paresis

132(0.7)

93(0.6)

39(1.6)

*< 0.001

 Plegia

59(0.3)

46(0.3)

13(0.5)

0.06

 Vertigo

500(2.7)

459(2.9)

41(1.6)

*< 0.001

 Seizure

64(0.3)

42(0.2)

23(0.9)

*< 0.001

 Insomnia

352(1.8)

326(1.9)

26(1)

*0.001

 Unconsciousness

872(4.5)

382(2.2)

490(19.1)

*< 0.001

 Headache

1644(9)

1509(9.5)

135(5.4)

*< 0.001

 Loss appetite

2042(11)

1731(10.8)

311(12.4)

*0.019

 Smell impairment

352(1.8)

326(1.9)

26(1)

*0.001

 Taste impairment

198(1)

181(1.1)

17(0.7)

0.059

 Skin sign

30(0.2)

27(0.2)

3(0.1)

0.55

 GI symptom

3534(19.1)

3112(19.4)

422(16.8)

*0.002

 Respiratory symptom

13,950(73.2)

11,870(71.8)

2080(82.1)

*< 0.001

 Nervous system

157(0.8)

111(0.7)

46(1.8)

*< 0.001

 Comorbidity

 Cardiovascular disease

1450(7.4)

1068(6.3)

382(14.9)

*< 0.001

 Hypertension

2236(11.4)

1715(10.)

521(20.4)

*< 0.001

 Diabetes mellitus

2267(11.6)

1746(10.3)

521(20.4)

*< 0.001

 Cancer

218(1.1)

155(0.9)

63(2.5)

*< 0.001

 COPD (Chronic Obstructive Pulmonary Disease)

308(1.6)

194(1.1)

114(4.5)

*< 0.001

 CKD (chronic kidney disease)

287(1.5)

212(1.2)

75(2.9)

*< 0.001

 Asthma

170(0.9)

133(0.8)

37(1.4)

*0.001

 Liver disease

35(0.2)

30(0.2)

5(0.2)

0.8

 Neurological disorders

157(0.8)

111(0.7)

46(1.8)

*< 0.001

 Hematology

55(0.3)

46(0.3)

9(0.4)

0.46

 HIV

8(0.0004)

7(0)

1(0)

0.96

 Congenital disorder

15(0.1)

13(0.1)

2(0.1)

0.97

 Pregnancy

123(0.6)

121(0.7)

2(1.6)

*< 0.001

 Smoking

359(1.8)

293(1.4)

66(2.6)

*0.003

 Opium

333(1.7)

242(1.4)

91(3.6)

*< 0.001

Early diagnosis based on

 Positive PCR

7828(40)

6575(38.7)

1253(49)

 

 Abnormal lung CT

6270(32.1)

5427(31.9)

843(33)

 

 Clinically admission

5464(27.9)

5003(29.4)

461(18)

*< 0.001

 Inpatients treatments

 Dialysis (N = 224/393)

155(54)

111(52.4)

44(58.7)

0.34

 Chemotherapy

48(38.7)

32(34)

16(53.3)

0.059

 Oxygen therapy

3949(31.2)

3110(29.1)

839(42.2)

*< 0.001

Hospital outcome

 Death

1787(9.1)

819(4.8)

968(37.8)

 

 Recovery

17,789(90.9)

16,198(95.2)

1591(62.2)

*< 0.001

  1. *P < 0.05.