Figure 3 | Scientific Reports

Figure 3

From: The immune cell landscape and response of Marek’s disease resistant and susceptible chickens infected with Marek’s disease virus

Figure 3

Viral transcription by individual, challenge status, genetic line, and cell type. (A) Viral transcripts per million in each library, separated by line and challenge status. Sample names are defined with first digit representing line 6 or 7, second digit representing the biological replicate, and the third character indicating whether the bird was infected with MDV (M) or an uninfected control (C). (B,C) Principal component analysis of bulk-collated gene expression data, showing PC1 versus PC2 (B) and PC1 versus PC3 (C). (D) Viral TPM values for each cell, grouped by cluster, shows signs of infection in most T cell clusters, as well as the plasma B and antigen-presenting myeloid clusters. (E,F) Viral TPMs for only cells from challenged birds, broken down by line, demonstrate that more clusters in the susceptible line show signs of infection than in the resistant line.

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