Figure 5

Genetic lines and cell types differ in their response to MDV infection. (A) Hierarchical clustering of each cell type in each line based on the log₂ fold change (log₂FC; MDV-infected compared to control) of all genes with significant differential expression in at least one contrast (n = 964). (B) Log₂FC across cell types for the top 25 differentially expressed genes (DEGs) in the resistant line (ADOL 6₃). (C) Log₂FC across cell types for the top 25 DEGs in the susceptible line (ADOL 7₂). The magnitude of log₂FC is shown according to the red-blue color scale. Cell type and genetic line are also annotated by color on the dendrogram and heatmaps. Significant log₂FCs (|log₂FC|≥ 1.0, p-adj < 0.01) are indicated by an asterisk and those genes with significance in both lines are shown in bold.