Figure 1 | Scientific Reports

Figure 1

From: The functional change of the P2X7R containing the Ala348 to Thr polymorphism is associated with the pathogenesis of gout

Figure 1

The functional effect of Ala348 to Thr in transfected HEK-293T cells. (A) P2X7-dependent ethidium+ uptake induced by 1 mM ATP (applied at arrow) in Ala348 to Thr compared with Wild-Type. (B) Mean ATP-induced ethidium+ bromide uptake was quantified by calculating the area under the dye uptake curve for cells expressing Ala348 to Thr. ***P < 0.001.

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