Figure 8
From: p130Cas is required for androgen-dependent postnatal development regulation of submandibular glands
Expansion of ER membrane during GCT differentiation was regulated by AR signaling and compromised in p130CasΔepi- mice. (A) Representative immunofluorescence staining images of SMG paraffin sections using anti-KDEL (grey) antibody. Nuclei were counterstained using Hoechst 33,342. Areas surrounded by red dotted lines indicate GCTs. Scale bars = 25 µm. (B) Representative immunofluorescence staining images of SMG paraffin sections from female p130Casflox/flox and p130CasΔepi- mice after vehicle or dihydrotestosterone injection using anti-KDEL (grey) antibody. Nuclei were counterstained using Hoechst 33,342. Areas surrounded by red dotted lines indicate GCTs. Scale bars = 25 µm.
