Table 1 The comparisons of MLCs, retinal and vascular parameters between DME eyes group and non-DME eyes group, PDR eyes and NPDR eyes in DME group and non-DME group.

Subjects, n (%)

151 (62.9)

89 (37.1)

–

97 (64.2)

54 (35.8)

–

58 (65.2)

31 (34.8)

–

Macular VD in SCP

 Central macular region

6.75 ± 3.75

4.10 ± 3.29

 < 0.001

6.52 ± 3.67

7.30 ± 3.91

0.227

3.67 ± 3.25

5.19 ± 3.22

0.047

 Inner layer macular region

13.93 ± 3.46

12.00 ± 3.76

 < 0.001

13.76 ± 3.19

14.18 ± 3.92

0.479

11.30 ± 3.48

13.40 ± 3.87

0.015

 Outer layer macular region

15.05 ± 2.99

13.66 ± 3.33

0.001

14.81 ± 2.88

15.46 ± 3.15

0.208

13.06 ± 3.29

14.91 ± 3.14

0.016

 Overall macular region

14.58 ± 2.98

13.03 ± 3.34

 < 0.001

14.34 ± 2.82

14.96 ± 3.26

0.231

12.37 ± 3.25

14.32 ± 3.21

0.012

Central macular thickness (um)

359.74 ± 130.43

194.57 ± 32.13

 < 0.001

368.07 ± 135.86

348.27 ± 119.45

0.382

186.69 ± 29.99

208.64 ± 30.50

0.002

Macular MLC count

781.79 ± 337.45

590.07 ± 314.15

 < 0.001

759.11 ± 328.72

837.85 ± 346.30

0.176

534.47 ± 267.49

675.00 ± 376.16

0.027

Area (mm²)

36.00 ± 0.04

36.00 ± 0.09

0.703

36.00 ± 0.04

36.00 ± 0.03

0.420

36.00 ± 0.07

36.01 ± 0.12

0.656

Macular MLC density (cells/mm²)

21.72 ± 9.37

16.39 ± 8.73

 < 0.001

21.09 ± 9.13

23.27 ± 9.62

0.177

16.42 ± 3.16

18.75 ± 10.45

0.026

Retinal HRF

18.04 ± 14.85

1.66 ± 2.10

 < 0.001

18.51 ± 15.19

17.20 ± 14.18

0.609

1.79 ± 2.02

1.42 ± 2.23

0.430

ELM/EZ integrity, n (%)

 < 0.001

0.002

–

 Intact

39 (25.8)

89 (100.0)

16 (16.5)

23 (42.6)

58

31

 Disrupted

101 (66.9)

0

73 (75.3)

28 (51.9)

0

0

 Absent

11 (7.3)

0

8 (8.2)

3 (5.5)

0

0

Leakage types in FFA, n (%)

–

0.495

 Focal leakage

39 (25.8)

0

22 (22.7)

17 (31.5)

 Diffuse leakage

48 (31.8)

0

32 (33.0)

16 (29.6)

 Mixed leakage

64 (42.4)

0

43 (44.3)

21 (38.9)