Table 3 Demographics per population and subtype.

From: Delineating COVID-19 subgroups using routine clinical data identifies distinct in-hospital outcomes

 

Training

Validation

All

Subtype 0

Subtype 1

Subtype 2

Subtype 3

All

Subtype 0

Subtype 1

Subtype 2

Subtype 3

Age [mean (std)]

70.0 (16.2)

67.0 (16.9)

69.2 (15.0)

74.3 (15.5)

73.0 (15.1)

69.5 (16.2)

66.2 (17.1)

71.8 (14.9)

73.9 (14.4)

71.4 (14.7)

Sex [% female)

59.8

55.2

63.4

60.6

67.0

61.6

59.3

68.2

63.0

59.8

Smoking status [% in each category]

N: 32.7

E: 20.0

C: 3.4

U: 43.4

N:32.8

E: 20.4

C: 3.2

U: 43.6

N: 36.1

E: 19.4

C: 3.7

U: 40.7

N: 30.5

E: 16.1

C: 2.6

U: 50.8

N: 31.3

E: 27.7

C: 4.8

U: 36.1

N: 31.7

E: 20.2

C: 4.6

U: 43.4

N: 31.7

E: 18.3

C: 4.2

U: 45.8

N: 31.1

E: 23.7

C: 6.5

U: 38.7

N: 32.5

E: 20.2

C: 3.5

U: 43.9

N: 31.9

E: 22.0

C: 5.5

U: 40.7

Mortality [% died]

32.9

18.6

38.2

52.8

38.5

29.9

18.9

32.7

47.1

37.4

Days to death [mean (std)]

125.5 (78.5)

149.3 (64.4)

115.4 (82.8)

93.3 (83.7)

116.1 (81.5)

130.3 (76.8)

149.1 (64.6)

124.4 (80.4)

101.5 (85.1)

117.6 (81.4)

Escalation [% escalated]

41.1

22.4

58

57.7

48.6

37.6

25.2

45.5

55.8

43.0

Days to escalation [mean (std)]

110.5 (83.9)

142.4 (70.2)

78.5 (86.8)

84.4 (83.7)

98.1 (85.0)

115.5 (83.4)

137.4 (73.9)

101.2 (87.0)

83.4 (86.6)

107.1 (84.7)

  1. Smoking status: N—never, E—ex-smoker, C—current smoker, U—unknown. No significant differences were found in any variable between the training and validation populations (using t-tests for continuous variables and chi-squared tests for nominal and binary variables).