Table 3 Multivariate analysis of CSS in PC patients.
From: Value of thyroid cancer history in the prognosis of pancreatic cancer: a SEER population-based study
Characteristics | HR (95% CI) | P value |
|---|---|---|
Age (Reference: < 68) | ||
68–79 | 1.259 (1.075–1.474) | 0.004 |
> 79 | 1.460 (1.192–1.789) | < 0.001 |
Sex (Reference: Female) | ||
Male | 1.017 (0.872–1.186) | 0.830 |
Race (Reference: Black) | ||
White | 0.756 (0.618–0.925) | 0.007 |
Other | 0.805 (0.627–1.034) | 0.090 |
Tumor size (Reference: < 2.6) | ||
2.6–3.5 | 1.175 (0.954–1.447) | 0.130 |
> 3.5 | 1.223 (0.992–1.508) | 0.060 |
Grade (Reference: Well differentiated) | ||
Moderately differentiated | 1.823 (1.336–2.488) | < 0.001 |
Poorly differentiated | 2.231 (1.574–3.162) | < 0.001 |
Undifferentiated | 2.284 (0.838–6.222) | 0.110 |
Unknown | 1.980 (1.445–2.714) | < 0.001 |
Radiotherapy (Reference: None/Unknown) | ||
Yes | 1.089 (0.915–1.297) | 0.340 |
Chemotherapy (Reference: None/Unknown) | ||
Yes | 0.570 (0.481–0.676) | < 0.001 |
Surgery (Reference: None/Unknown) | ||
Yes | 0.441 (0.348–0.559) | < 0.001 |
AJCC T status (Reference: T1) | ||
T2 | 1.607 (1.028–2.513) | 0.037 |
T3 | 1.888 (1.221–2.919) | 0.004 |
T4 | 1.665 (1.050–2.639) | 0.030 |
Unknown | 2.607 (1.579–4.303) | < 0.001 |
AJCC N status (Reference: N0) | ||
N1 | 1.235 (1.065–1.433) | 0.005 |
Unknown | 1.383 (0.944–2.026) | 0.096 |
AJCC M status (Reference: M0) | ||
M1 | 1.866 (1.568–2.221) | < 0.001 |
Primary site (Reference: Head of pancreas) | ||
Body of pancreas | 0.861 (0.700–1.059) | 0.160 |
Tail of pancreas | 0.903 (0.720–1.133) | 0.380 |
Pancreatic duct | 1.438 (0.986–2.098) | 0.059 |
Other specified parts of pancreas | 0.958 (0.741–1.238) | 0.740 |
Overlapping lesion of pancreas | 1.069 (0.812–1.407) | 0.640 |
Pancreas, NOS | 0.864 (0.583–1.280) | 0.470 |
Histological subtype (Reference: Adenocarcinoma) | ||
Infiltrating duct carcinoma | 1.288 (1.061–1.564) | 0.011 |
Neuroendocrine carcinoma | 0.195 (0.130–0.292) | < 0.001 |
Other | 0.640 (0.476–0.860) | 0.003 |
Prior thyroid cancer history (Reference: without) | ||
With | 0.722 (0.542–0.961) | 0.026 |
