Figure 2

No correlation between the PCSK9 protein and antibody levels were observed neither HDs nor DM. Serum concentration of the convertase subtilisin/kexin type 9 antibodies (PCSK9-Abs) and PCSK-protein were measured by amplified luminescence proximity homogeneous assay-linked immunosorbent assay (AlphaLISA). Scatter dot plots of PCSK9-Abs versus PCSK9 protein in HD group (a) and DM group (b) are shown. Correlation coefficient (r), test statistic (t), and p-value (p) were calculated by Spearman's correlation analysis. HD: Healthy donors (a), DM: patients with diabetes (b), a.c: Alpha counts.