Table 1 Descriptive statistics that indicate the importance of each symptom.

From: Self-report symptom-based endometriosis prediction using machine learning

Symptom

Not diagnosed

Diagnosed

Absolute mean diff

P-value

2-test)

Importance (AdaBoost)

Menstrual pain (dysmenorrhea)

0.05 (0.05)

0.76 (0.18)

0.71

0.0

0.04

Cramping

0.23 (0.17)

0.83 (0.14)

0.60

2.03E−289

0.024

Painful cramps during period

0.07 (0.07)

0.67 (0.22)

0.60

3.87E−221

0.032

Fatigue/chronic fatigue

0.11 (0.1)

0.7 (0.21)

0.59

5.58E−211

0.03

Heavy/Extreme menstrual bleeding

0.2 (0.16)

0.77 (0.17)

0.59

3.11E−215

0.054

Pelvic pain

0.19 (0.15)

0.76 (0.18)

0.57

0.0

0.034

Abdominal pain/pressure

0.11 (0.1)

0.67 (0.22)

0.56

1.28E−123

0.018

Painful/Burning pain during intercourse (dyspareunia)

0.12 (0.11)

0.67 (0.22)

0.55

0.0

0.022

Back pain

0.28 (0.2)

0.77 (0.18)

0.49

1.76E−112

0.016

Bloating

0.14 (0.12)

0.62 (0.24)

0.47

0.0

0.022

Lower back pain

0.15 (0.12)

0.62 (0.24)

0.47

7.74E−146

0.016

Sharp/stabbing pain

0.08 (0.08)

0.54 (0.25)

0.45

0.0

0.004

Painful bowel movements

0.05 (0.05)

0.51 (0.25)

0.45

5.97E−154

0.038

Pain/chronic pain

0.16 (0.13)

0.61 (0.24)

0.45

1.25E−55

0.022

Decreased energy/exhaustion

0.14 (0.12)

0.58 (0.24)

0.44

3.07E−184

0.002

Stomach cramping

0.09 (0.08)

0.53 (0.25)

0.44

0.0

0

Menstrual clots

0.04 (0.04)

0.47 (0.25)

0.42

4.84E−29

0

Ovarian cysts

0.01 (0.01)

0.43 (0.25)

0.42

0.0

0.022

Irregular/missed periods

0.09 (0.08)

0.49 (0.25)

0.40

3.02E−155

0.044

Painful ovulation

0.12 (0.11)

0.53 (0.25)

0.40

1.96E−237

0.028

Nausea

0.17 (0.14)

0.56 (0.25)

0.39

2.74E−14

0.006

Extreme/severe pain

0.11 (0.1)

0.5 (0.25)

0.39

1.58E−165

0.022

Pain after intercourse

0.07 (0.06)

0.45 (0.25)

0.39

1.23E−42

0

Hormonal problems

0.07 (0.06)

0.42 (0.24)

0.36

2.64E−115

0.026

Anxiety

0.18 (0.15)

0.53 (0.25)

0.35

8.22E−188

0.016

Cysts (unspecified)

0.02 (0.02)

0.37 (0.23)

0.35

1.90E−68

0.02

Constipation/chronic constipation

0.04 (0.04)

0.39 (0.24)

0.35

1.97E−58

0.016

IBS-like symptoms

0.02 (0.02)

0.36 (0.23)

0.34

1.30E−208

0.034

Vaginal pain/pressure

0.09 (0.08)

0.42 (0.24)

0.33

1.22E−188

0.02

Mood swings

0.2 (0.16)

0.53 (0.25)

0.32

3.06E−70

0.018

Abdominal cramps during Intercourse

0.06 (0.05)

0.38 (0.23)

0.32

0.0

0.02

Digestive/GI problems

0.06 (0.05)

0.36 (0.23)

0.30

2.71E−122

0

Long menstruation

0.05 (0.05)

0.35 (0.23)

0.30

1.18E−30

0.012

Depression

0.2 (0.16)

0.5 (0.25)

0.30

5.22E−59

0.002

Acne/pimples

0.09 (0.09)

0.39 (0.24)

0.29

5.47E−244

0

Infertility

0.06 (0.05)

0.33 (0.22)

0.27

7.23E−179

0.02

Diarrhea

0.17 (0.14)

0.44 (0.25)

0.27

0.0

0

Anaemia/iron deficiency

0.07 (0.06)

0.33 (0.22)

0.27

9.81E−123

0.002

Feeling sick

0.2 (0.16)

0.46 (0.25)

0.26

1.59E−51

0.02

Painful urination

0.06 (0.06)

0.32 (0.22)

0.26

2.74E−141

0

Leg pain

0.2 (0.16)

0.45 (0.25)

0.25

9.12E−282

0.004

Irritable Bowel Syndrome (IBS)

0.06 (0.05)

0.3 (0.21)

0.25

5.28E−43

0.016

Hip pain

0.15 (0.12)

0.39 (0.24)

0.24

7.79E−91

0.002

Insomnia/sleeplessness

0.17 (0.14)

0.41 (0.24)

0.24

0.0

0

Headaches

0.25 (0.19)

0.49 (0.25)

0.23

2.45E−42

0.02

Dizziness

0.16 (0.13)

0.39 (0.24)

0.23

2.17E−12

0.008

Bowel pain

0.14 (0.12)

0.35 (0.23)

0.22

9.70E−21

0.038

Fertility issues

0.05 (0.05)

0.23 (0.18)

0.18

2.22E−08

0.022

Migraines

0.3 (0.21)

0.46 (0.25)

0.16

2.34E−218

0.002

Vomiting/constant vomiting

0.1 (0.09)

0.26 (0.19)

0.16

1.61E−191

0.018

Loss of appetite

0.2 (0.16)

0.34 (0.22)

0.14

6.34E−45

0.03

Constant bleeding

0.03 (0.03)

0.17 (0.14)

0.13

3.91E−168

0.028

Syncope (fainting, passing out)

0.01 (0.01)

0.14 (0.12)

0.13

3.67E−191

0

Fever

0.23 (0.18)

0.12 (0.11)

0.11

8.67E−44

0.024

Abnormal uterine bleeding

0.04 (0.04)

0.13 (0.11)

0.09

3.71E−104

0.042

Malaise/Sickness

0.08 (0.07)

0.16 (0.13)

0.09

1.74E−14

0.024

  1. For each symptom we present the percentage (mean and variance in parenthesis) of undiagnosed and diagnosed women who experience the symptom, the absolute mean (frequency) difference between undiagnosed and diagnosed women, and whether the difference is significant (chi-square test, p-value < 0.01). The rightmost column presents the importance of each symptom according to the AdaBoost model, which is detailed below.