Table 3 In-vitro CA IX inhibitory activity for compounds 3 and 11.

From: Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer

Compound

CA IX (IC50 uM)*

3

0.336 ± 0.016

11

0.128 ± 0.006

Dorzolamide

0.122 ± 0.002

  1. *Results are average of triplicate experiments ± SEM.