Table 4 The lesion scoring of renal tissues of butylated hydroxyl anisole (BHA), potassium sorbate (PS), sodium benzoate (SB), boric acid (BA), or calcium propionate (CP)-treated rats.
Parameter | Treatment | |||||
|---|---|---|---|---|---|---|
Control | BHA | PS | SB | BA | CP | |
A. Macroscopic appearance | ||||||
1. Congestion and enlargement | − | ++ | ++ | − | + | − |
2. Small size and paleness | − | − | − | ++ | − | +++ |
B. Microscopic appearance | ||||||
1. Degenerative renal tubules changes | − | ++ | +++ | +++ | +++ | +++ |
2. Tubular atrophy | − | + | + | +++ | ++ | +++ |
3. Dilated tubules with degenerated cells and leucocytic infiltrations | − | − | − | ++ | − | +++ |
4. Hyaline cast | − | + | + | +++ | + | +++ |
5. Shrinkage of glomeruli | − | + | ++ | +++ | ++ | +++ |
6. Congestion of glomerular tuft | − | ++ | ++ | +++ | ++ | + |
7. Interstitial nephritis | − | ++ | + | +++ | + | +++ |
8. Interstitial fibrosis | − | − | − | + | − | +++ |
9. Interstitial b.v. Congestion | − | +++ | +++ | +++ | +++ | + |
10. Edema | − | ++ | ++ | + | ++ | − |
