Figure 7
Patients with high and low risk scores have different immune status and scores for immune infiltrating cells and immune-related functions in the high-risk and low-risk groups. (A) Genome-wide distribution of patients. (B) OS-related gene sets. (C) OS-related lncRNAs. (D) Seven-lncRNA prognostic signature of OS. (E) Infiltration levels of 16 immune cells in the high-risk and low-risk groups using the ssGSEA algorithm. (F) Correlation of predictive signature with 13 immune-related functions. OS, oxidative stress; lncRNA, long non-coding RNA; ssGSEA, single-sample gene set enrichment analysis; aDCs, activated dendritic cells; iDCs, immature dendritic cells; NK, natural killer; pDCs, plasmacytoid dendritic cells; Tfh, T follicular helper cells; Th1, T helper cell type 1; TIL, tumour-infiltrating lymphocytes; Treg, regulatory T cell; APC, antigen presenting cell; CCR, cytokine–cytokine receptor interaction; HLA, human leukocyte antigen; MHC, major histocompatibility complex; IFN, interferon. *p < 0.05; **p < 0.01; ***p < 0.001; ns, not significant.
