Table 3 Baseline demographic and clinical characteristics of patient groups. IgAN, IgA nephropathy; DC, Disease control; NC, Normal control; GFR, Estimated glomerular filtration rate.
Group | Confirmation cohort | Validation cohort | |||
|---|---|---|---|---|---|
IgAN | NC | IgAN | DC | NC | |
no. of subjects | 30 | 30 | 144 | 100 | 67 |
Sex (M: F) | 17:13 | 17:13 | 78:66 | 55:45 | 33:34 |
Age (year) | 36.30 ± 9.75 | 36.92 ± 10.27 | 36.51 ± 10.42 | 43.72 ± 14.19 | 38.50 ± 9.16 |
Proteinuria (g/day) | 0.96 (0.81–1.41) | – | 1.35 (0.78–2.22) | 3.33 (1.71–5.45) | – |
Serum creatinine (umol/L) | 97.55 (78.60–133.30) | – | 99.25 (80.30–125.18) | 73.85 (62.03–113.83) | – |
eGFR (ml/min/1.73m2) | 70.17 ± 28.98 | – | 72.00 ± 27.44 | 97.55(60.94–114.11) | – |