Table 1 Demographic and clinical characteristics of all dMMR patients.
Total (No. %) | Surgery alone group (No. %) | Chemotherapy group (No. %) | p | |
|---|---|---|---|---|
Sex | 0.032 | |||
Male | 157 (51.3%) | 63 (44.7%) | 94 (57.0%) | |
Female | 149 (48.7%) | 78 (55.3%) | 71 (43.0%) | |
Age | 0.087 | |||
< 60 | 120 (39.2%) | 48 (34.0%) | 72 (43.6%) | |
≥ 60 | 186 (60.8%) | 93 (66.0%) | 93 (56.4%) | |
Depth of tumor invasion (T) | 0.393 | |||
T1 | 12 (3.9%) | 8 (5.7%) | 4 (2.4%) | |
T2 | 15 (4.9%) | 7 (5.0%) | 8 (4.8%) | |
T3 | 211 (69.0%) | 92 (65.2%) | 119 (72.1%) | |
T4 | 68 (22.2%) | 34 (24.1%) | 34 (20.6%) | |
Positive lymph nodes (N) | 0.867 | |||
0 | 219 (71.5%) | 102 (72.3%) | 117 (70.9%) | |
1–3 | 58 (19.0%) | 25 (17.7%) | 33 (20.0%) | |
≥ 4 | 29 (9.5%) | 14 (9.9%) | 15 (9.1%) | |
TNM | 0.601 | |||
1 | 25 (8.2%) | 15 (10.6%) | 10 (6.1%) | |
2 | 193 (63.1%) | 86 (61.0%) | 107 (64.8%) | |
3 | 75 (24.5%) | 33 (23.4%) | 42 (25.5%) | |
4 | 13 (4.2%) | 7 (5.0%) | 6 (3.6%) | |
Histologic grade | 0.820 | |||
Low (1/2) | 146 (47.7%) | 70 (49.6%) | 76 (46.1%) | |
High (3/4) | 110 (35.9%) | 49 (34.8%) | 61 (37.0%) | |
Special type | 50 (16.3%) | 22 (15.6%) | 28 (17.0%) | |
Location | 0.024 | |||
Proximal colon | 208 (68.0%) | 105 (74.5%) | 103 (62.4%) | |
Distal colon | 99 (32.0%) | 36 (25.5%) | 63 (37.6%) | |
Operation | 0.432 | |||
Open surgery | 219 (71.6%) | 104 (73.8%) | 115 (69.7%) | |
Laparoscopic | 87 (28.4%) | 37 (26.2%) | 50 (30.3%) | |
Total | 306 (100%) | 141 (46.1%) | 165 (53.9%) | |