Table 1 Demographic characteristics and clinical data of the study cohort at baseline.

From: The role of Klotho and FGF23 in cardiovascular outcomes of diabetic patients with chronic limb threatening ischemia: a prospective study

Number of patients

220

Men/female, n

150:70

Age, years ± SD

71.3 ± 9.2

Diabetes duration, years ± SD

12.4 ± 4.6

BMI, Kg/m2 ± SD

29.5 ± 3.0

Smoking (current), n (%)

61 (27.7)

Smoking (former), n (%)

68 (30.9)

Never smoked, n (%)

91 (41.4)

Hypertension, n (%)

120 (54.5)

Hypercholesterolemia, n (%)

100 (45.4)

CAD, n (%)

102 (46.4)

CVD, n (%)

45 (20.4)

Lipid-lowering agent

178 (80.9)

ACE inhibitor or ARB

165 (75.0)

ABI, ± SD

0.39 ± 0.1

Rutherford II-4, n (%)

121 (55.0)

Rutherford III-5, n (%)

99 (45.0)

WIfI010, n (%)

99 (45.0)

WIfI020, n (%)

35 (15.9)

WIfI110, n (%)

62 (28.2)

WIfI120, n (%)

107 (48.6)

HbA1c, % ± SD

8.8 ± 1.5

FBG, mg/dL ± SD

114.1 ± 19.8

Total cholesterol, mg/dL ± SD

204.1 ± 29.3

LDL cholesterol, mg/dL ± SD

100.7 ± 19.4

Triglycerides, mg/dL ± SD

212.2 ± 36.9

Creatinine, mg/dL ± SD

1.4 ± 0.4

eGFR, mL/min/1.73m2 ± SD

64.4 ± 14.6

Ca, mg/dL ± SD

9.5 ± 0.8

Ph, mg/dL ± SD

3.7 ± 0.8

Vitamin D, ng/mL ± SD

48.5 ± 15.9

Klotho, pg/mL ± SD

403.1 ± 179.3

FGF23 pg/mL ± SD

59.4 ± 17.5

  1. Data are reported as means (standard deviation) for continuous variables and numbers (percentages) for categorical variables. BMI Body Mass Index; CAD Coronary Artery Disease; CVD Cerebrovascular Disease; ACE angiotensin-converting enzyme; ARB angiotensin receptor blocker; ABI Ankle Brachial Index; WIfI Wound, Ischemia, foot Infection; FBG Fasting Blood Glucose; eGFR estimated Glomerular Filtration Rate; Ca Calcium; Ph Phosphorus; FGF23 Fibroblast Growth Factor 23.