Figure 3 | Scientific Reports

Figure 3

From: Association of SLC11A1 polymorphisms with anthropometric and biochemical parameters describing Type 2 Diabetes Mellitus

Figure 3

Web-based analysis of the impact of studied intronic variants on the pattern of splicing processes using the SpliceAid database. rs3731864 mutant (A), rs3731864 wild-type (B), rs3731865 mutant (C), rs3731865 wild-type (D). G to A substitution in the rs3731864 position disrupts the binding sites of some splicing factors including SC35, SF2/ASF, hnRNP f, hnRNP H3, hnRNP H1, and hnRNP H2. On the contrary, nucleotid change on the position of rs3731865 creates binding site for SF2/ASF and hnRNP H3 facors.

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