Table 4 Interaction analysis of SLC11A1 polymorphisms on T2DM risk.
rs3731864 G/A | rs3731865 C/G | rs17235416 + TGTG/− TGTG | Case (%) | Control (%) | OR (95% CI) | p-value |
|---|---|---|---|---|---|---|
GG | CC | + TGTG/+ TGTG | 255 (63.8) | 235 (58.8) | 1 [reference] | |
GA | CC | + TGTG/+ TGTG | 26 (6.5) | 55 (13.8) | 0.43 (0.26–0.71) | < 0.001 |
GG | CG | + TGTG/+ TGTG | 83 (20.8) | 46 (11.5) | 1.66 (1.11–2.48) | 0.013 |
GG | CC | + TGTG/− TGTG | 17 (4.3) | 31 (7.8) | 0.50 (0.27–0.94) | 0.028 |
GA | CG | + TGTG/+ TGTG | 9 (2.3) | 12 (3.0) | 0.70 (0.29–1.67) | 0.410 |
AA | CC | + TGTG/+ TGTG | 3 (0.8) | 5 (1.3) | 0.55 (0.13–2.34) | 0.415 |
GA | CC | + TGTG/− TGTG | 2 (0.5) | 5 (1.3) | 0.37 (0.07–1.92) | 0.218 |
GG | CG | + TGTG/− TGTG | 2 (0.5) | 5 (1.3) | 0.37 (0.07–1.92) | 0.218 |
GG | GG | + TGTG/+ TGTG | 2 (0.5) | 2 (0.5) | 0.92 (0.13–6.60) | 0.935 |
GG | CG | − TGTG/− TGTG | 1 (0.3) | 1 (0.3) | 0.92 (0.05–14.82) | 0.954 |