Table 2 Random intercept linear mixed effect models examining comparisons between groups in fasting insulin and HOMA-IR over time.

From: Effects of bariatric surgery and dietary intervention on insulin resistance and appetite hormones over a 3 year period

 

Annual change in insulin level (mU/L)

Annual change in HOMA-IR in level (units)

 

Difference in insulin level between surgical and DIET groups (95% CI)

Difference in HOMA-IR level between surgical and DIET groups (95% CI)

 

0–12 months

12–36 months

0–12 months

12–36 months

Study groups

  

Sensitivity analysis

  

Sensitivity analysis

Diet

Ref.

Ref.

Ref.

Ref.

Ref.

Ref.

LAGB

− 3.7 (− 9.5, 2.1)

− 7.4 (− 12.2, − 2.5)

 

− 2.6 (− 4.9, − 0.3)

− 2.6 (− 4.1, − 1.1)

 

GS

− 1.8 (− 6.8, 3.1)

− 7.2 (− 11.3, − 3.1)

− 2.6 (− 6.2, 1.0)

− 2.0 (− 3.9, − 0.03)

− 2.6 (− 3.9, − 1.3)

− 1.3 (− 2.4, − 0.2)

RYGB

− 6.9 (− 13.4, − 0.5)

− 12.4 (− 17.7, − 7.1)

− 7.9 (− 12.5, − 3.3)

− 2.8 (− 5.3, − 0.3)

− 3.7 (− 5.4, − 2.1)

− 2.4 (− 3.8, − 1.0)

  1. Data presented as annual change in Insulin level (mU/L/year) and HOMA-IR levels (units) with the corresponding 95% CI for two periods: baseline and 12 months, and between 12- and 36- months post intervention. RYGB Roux-en-Y gastric bypass, GS gastric sleeve, LAGB laparoscopic adjustable gastric banding. Boldface indicates statistical significance.
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