Table 2 Incidence and risk of clinical outcomes.

From: Impact of coronary artery revascularization on long-term outcome in hypertrophic cardiomyopathy patients: a nationwide population-based cohort study

 

HCM group

Non-HCM control group

 

Event/N

IR-per 1000 p-y

Event/N

IR-per 1000 p-y

Unadjusted

HR (95% CI)

P

*Adjusted

HR (95% CI)

P

PS-Matched

HR (95% CI)

P

All-cause death

99/431

53.6

351/1968

36.6

1.45 (1.16–1.82)

0.001

1.63 (1.29–2.07)

 < 0.001

1.78 (1.29–2.46)

0.001

Cardiovascular death

55/431

29.8

142/1968

14.8

1.95 (1.43–2.67)

 < 0.001

2.27 (1.63–3.15)

 < 0.001

3.15 (1.87–5.32)

 < 0.001

Sudden cardiac death

29/431

15.8

71/1968

7.4

2.07 (1.34–3.18)

0.001

1.90 (1.20–3.01)

0.007

2.20 (1.16–4.18)

0.016

Ischemic stroke

36/431

20.3

72/1968

7.7

2.58 (1.73–3.86)

 < 0.001

2.38 (1.55–3.64)

 < 0.001

4.83 (2.24–10.42)

 < 0.001

Hospitalization due to heart failure

122/431

78.7

434/1968

50.4

1.51 (1.23–1.84)

 < 0.001

1.41 (1.14–1.74)

0.002

1.40 (1.07–1.82)

0.014

Ventricular fibrillation/tachycardia

20/431

11.0

44/1968

4.6

2.28 (1.34–3.87)

0.002

1.63 (0.93–2.87)

0.090

1.74 (0.84–3.58)

0.135

Myocardial infarction

12/431

6.6

95/1968

10.3

0.61 (0.33–1.11)

0.106

0.66 (0.35–1.24)

0.200

0.74 (0.35–1.55)

0.425

Repeat revascularization

60/431

35.5

307/1968

36.2

0.94 (0.71–1.24)

0.673

0.91 (0.68–1.22)

0.524

0.79 (0.56–1.11)

0.179

  1. *Multivariable Cox regression model included age, sex, low income, revascularization due to acute MI, revascularization after coronary CT angiography, hypertension, diabetes mellitus, dyslipidemia, atrial fibrillation, previous stroke, and congestive heart failure.
  2. Abbreviations: CI, confidence interval; CT, computed tomography; HCM, hypertrophic cardiomyopathy; HR, hazard ratio; IR, incidence rate; MI, myocardial infarction; PS, propensity score; p-y-person-years; VF, ventricular fibrillation; VT, ventricular tachycardia.
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