Figure 5
From: Estimation of silent phenotypes of calf antibiotic dysbiosis
(a) The ELA interaction network shows the significant relationships in the extended pairwise maximum entropy model fitted to the observational data. Components were selected by linear discriminant analysis and association analysis. The bacteria selected by both analyses are underlined. The blue and red lines show positive and negative relationships, respectively. The abbreviations are as follows: E: family Erysipelotrichaceae; L: family Lachnospiraceae; GLU: serum glucose; NEFA: serum nonesterified free fatty acid; butyrate: fecal butyric acid; propionate: fecal propionic acid; T-Cho: serum total cholesterol. (b) The calculated causal relationship of the components strongly linked with butyrate is visualized by linear non-Gaussian acyclic model (DirectLiNGAM) analysis. The amounts of change (d 3, 30, and 60) with respect to the values at d 3 of the components aligned with butyrate (green letters) (a) were used for the calculation. The arrow shows the trend of the causal relationship. The number shows the value of the causal contribution calculated by the DirectLiNGAM analysis. The minus and plus values show negative and positive causal contributions, respectively.
