Figure 9 | Scientific Reports

Figure 9

From: A Doppler-exclusive non-invasive computational diagnostic framework for personalized transcatheter aortic valve replacement

Figure 9

Changes in valve dynamics and global hemodynamics in patient #3 between baseline and 90-day post-TAVR. (a) Transient distribution of major principal stress at six time phases of the cardiac cycle: early systole (start of valve opening), early to peak systole (valve opening), peak systole (fully open), peak to late systole (valve closure), early diastole (closed configuration) and late diastole (closed configuration); (b) transient distribution of the von Mises stress at six time phases of the cardiac cycle: early systole(start of valve opening), early to peak systole(valve opening), peak systole (fully open), peak to late systole (valve closure), early diastole (closed configuration) and late diastole (closed configuration); (c) Global hemodynamics: LV workload; aorta and LV pressures in both pre- and post-intervention states. Patient #3: Pre-TAVR: severe aortic stenosis (EOA = 0.6 cm2), dyslipidemia, coronary artery disease, mild to moderate mitral regurgitation and chronic AF, ejection fraction: 29%, brachial pressures: 61 and 107 mmHg; Post-TAVR: aortic valve (EOA = 2.0 cm2), mild mitral regurgitation and dyslipidemia, ejection fraction: 34%, brachial pressures: 86 and 130 mmHg.

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