Table 1 Mean responses (μV) for the a-wave, b-wave, cones, and 12-Hz flicker tests for control and treated eyes (n = 5 in each group).
From: Micro-abnormalities in the retina and choroid induced by anti-CTLA4 treatment
Averaged amplitude | Stimulation (log cds/m2) | Controls | CTLA4 treated | P value | |
|---|---|---|---|---|---|
Dark adaptation | a-wave | − 1 | 69.684 ± 27.077 | 35.197 ± 20.377 | 0.0011 |
0 | 194.333 ± 85.923 | 104.414 ± 55.772 | 0.0034 | ||
1 | 281.616 ± 65.368 | 195.166 ± 78.976 | 0.008 | ||
b-wave | − 4 | 80.471 ± 32.803 | 38.453 ± 23.261 | 0.0008 | |
− 3 | 163.957 ± 78.632 | 79.989 ± 38.500 | 0.0012 | ||
− 2 | 276.167 ± 1 17.513 | 119.953 ± 57.774 | 0.0001 | ||
− 1 | 295.241 ± 97.916 | 143.653 ± 57.726 | < 0.0001 | ||
0 | 347.262 ± 137.451 | 192.749 ± 85.987 | 0.0017 | ||
1 | 479.250 ± 154.587 | 292.653 ± 130.706 | 0.003 | ||
Light adaptation | 0 | 29.590 ± 5.616 | 18.422 ± 9.698 | 0.0055 | |
0.5 | 64.158 ± 24.909 | 32.024 ± 20.167 | 0.0014 | ||
1 | 114.380 ± 37.196 | 71.987 ± 44.556 | 0.0193 | ||
1.5 | 121.718 ± 37.056 | 75.883 ± 42.771 | 0.0101 | ||
12 Hz Flicker | 0.5 | 80.471 ± 32.816 | 38.453 ± 23.274 | 0.0152 |
