Table 1 Phylum level proportions of gut microbiota.

From: Green tea extract prevents CPT-11-induced diarrhea by regulating the gut microbiota

Phylum

Cont.

CPT-11

HST

GTE

Firmicutes

42.7 ± 2.5

33.4 ± 4.9

33.4 ± 7.7

28.8 ± 3.2**

Bacteroidetes

3.2 ± 0.2

15.8 ± 4.7*

3.0 ± 1.4†

22.5 ± 0.8***

Proteobacteria

–

29.2 ± 10.8*

1.2 ± 0.6†

14.3 ± 6.8*

Verrucomicrobia

0.1 ± 0.1

2.0 ± 1.0

2.8 ± 1.8

10.0 ± 2.6*,†

Actinobacteria

0.4 ± 0.1

0.7 ± 0.1

0.9 ± 0.3

2.5 ± 0.9*,†

Deferribacteres

–

–

2.1 ± 0.8*,†

0.1 ± 0.0**,†

Reject hit

53.5 ± 2.3

18.9 ± 8.9

56.6 ± 8.7

21.8 ± 6.0

  1. Rats were administered CPT-11 or lactic acid buffer intravenously for 4 days, and HST or GTE was administered in combination. The relative abundance at the phylum level in the gut microbiota was measured by next-generation sequencing. “–” indicates that the value is greater than 0 and less than 0.1 (mean ± S.D., n = 3, *p < 0.05, **p < 0.01, ***p < 0.001 vs. Cont., †p < 0.05 vs. CPT-11).
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