Figure 6
Example of treatment deviation caused by anatomical changes. (a) The axial, sagittal and coronal plane of the example patient with the average intensity projection of the 4D planning CT (yellow) overlaid on the repeat CT (blue). The target volume contoured by the treating oncologist on both CTs are visible as red contours. Both a shift and deformation of the target volume with corresponding change in tissue densities can be observed. The lungs are larger on the planning compared to the repeat CT indicating a shallower breathing pattern during acquisition of the latter. (b) PG and FN production, both from MC truth and reconstructed with MLEM, from the planning CT (top) and when produced in the week 1 CT, overlaid on the planning CT (bottom).
