Table 5 Factors associated with 30-day poor outcomes in patients with aneurysmal subarachnoid haemorrhage: logistic regression analyses.

From: Predictive validity of the prognosis on admission aneurysmal subarachnoid haemorrhage scale for the outcome of patients with aneurysmal subarachnoid haemorrhage

Factors

Univariable logistic regression analysesa

Multivariable logistic regression analysesb

OR

95% CI for OR

p value

AOR

95% CI for AOR

p value

Lower

Upper

Lower

Upper

Demographics

 Age ≥ 60 years

2.407

1.586

3.654

< 0.001

3.181

1.393

7.262

0.006

Risk factors of aneurysmal SAH

 Hypertension

2.056

1.354

3.122

0.001

NA

NA

NA

NA

Comorbidities

 Diabetes mellitus

3.751

1.669

8.433

0.001

NA

NA

NA

NA

Neuroimaging findings on admission

 Location of blood within the subarachnoid space:

  Basal cistern

2.685

1.728

4.173

< 0.001

NA

NA

NA

NA

  Sylvian fissure

2.981

1.125

7.900

0.028

NA

NA

NA

NA

  Interhemispheric fissure

1.960

1.207

3.183

0.007

NA

NA

NA

NA

  Interpeduncular fossa

3.254

1.995

5.308

< 0.001

2.673

1.106

6.460

0.029

  Suprasellar cistern

1.929

1.221

3.047

0.005

NA

NA

NA

NA

  Ambient cistern

3.054

1.902

4.906

< 0.001

NA

NA

NA

NA

  Quadrigeminal cistern

5.141

3.270

8.085

< 0.001

NA

NA

NA

NA

 IVH

3.013

1.847

4.914

< 0.001

NA

NA

NA

NA

 ICH

1.860

1.142

3.029

0.013

NA

NA

NA

NA

 Aneurysm locations

  PCoA aneurysm

0.554

0.299

1.026

0.061

NA

NA

NA

NA

  VA aneurysm

3.341

1.265

8.820

0.015

NA

NA

NA

NA

Severity of aneurysmal SAH on admission

 PAASH grade of III–V

15.823

9.480

26.409

< 0.001

11.023

4.544

26.740

< 0.001

 WFNS grade of IV–V

15.770

9.547

26.048

< 0.001

NA

NA

NA

NA

 H&H grade of IV–V

14.612

8.887

24.025

< 0.001

NA

NA

NA

NA

Aneurysm repairs and other treatments

 Aneurysm repairs

  No aneurysm repair

Reference

  

< 0.001

Reference

  

< 0.001

  Endovascular coiling

0.009

0.003

0.027

< 0.001

0.008

0.002

0.032

< 0.001

  Surgical clipping

0.020

0.007

0.059

< 0.001

0.015

0.004

0.056

< 0.001

 Nimodipine

0.076

0.028

0.202

< 0.001

NA

NA

NA

NA

Complications

 Rebleeding

7.868

2.537

24.396

< 0.001

21.817

4.641

102.548

< 0.001

 DCI

7.316

2.848

18.792

< 0.001

17.563

4.618

66.789

< 0.001

 Acute hydrocephalus

3.134

2.034

4.830

< 0.001

2.150

0.938

4.931

0.071

 Pneumonia

4.091

2.295

7.292

< 0.001

4.182

1.632

10.716

0.003

 Constant

    

0.801

  

0.753

  1. AOR adjusted odds ratio, CI confidence interval, DCI delayed cerebral ischemia, H&H Hunt and Hess, ICH intracerebral haemorrhage, IVH intraventricular haemorrhage, mRS modified Rankin Scale, NA not available, OR odds ratio, PAASH Prognosis on Admission of Aneurysmal Subarachnoid Haemorrhage, PCoA posterior communicating artery, SAH subarachnoid haemorrhage, VA vertebral artery, WFNS World Federation of Neurosurgical Societies.
  2. aEach variable of the demographics, risk factors for aneurysmal SAH, comorbidities, initial clinical, neuroimaging and laboratory characteristics, the severity of aneurysmal SAH (i.e., the grades of PAASH, WFNS, and H&H grading scales that were either greater than or equal to the cut-off value) on admission, treatments, and complications was analysed in the univariable logistic regression model and was considered in the multivariable logistic regression model if the p value was < 0.05 in univariable logistic regression analysis, as well as clinically crucial factors.
  3. bAll selected variables were included in the multivariable logistic regression model with the stepwise backward elimination method. Variables, then, were deleted stepwise from the full model until all remaining variables were independently associated with poor outcomes.
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