Table 6 Factors associated with 90-day poor outcomes in patients with aneurysmal subarachnoid haemorrhage: logistic regression analyses.

From: Predictive validity of the prognosis on admission aneurysmal subarachnoid haemorrhage scale for the outcome of patients with aneurysmal subarachnoid haemorrhage

Factors

Univariable logistic regression analysesa

Multivariable logistic regression analysesb

OR

95% CI for OR

p value

AOR

95% CI for AOR

p value

Lower

Upper

Lower

Upper

Demographics

 Age ≥ 60 years

2.581

1.691

3.939

< 0.001

3.495

1.518

8.049

0.003

Risk factors of aneurysmal SAH

 Hypertension

2.133

1.400

3.250

< 0.001

NA

NA

NA

NA

Comorbidities

 Diabetes mellitus

3.986

1.772

8.968

0.001

3.786

0.856

16.746

0.079

Neuroimaging findings on admission

 Location of blood within the subarachnoid space:

  Basal cistern

2.718

1.738

4.251

< 0.001

NA

NA

NA

NA

  Sylvian fissure

2.811

1.060

7.454

0.038

NA

NA

NA

NA

  Interhemispheric fissure

2.063

1.257

3.385

0.004

NA

NA

NA

NA

  Interpeduncular fossa

3.206

1.953

5.264

< 0.001

NA

NA

NA

NA

  Suprasellar cistern

1.882

1.186

2.986

0.007

NA

NA

NA

NA

  Ambient cistern

2.990

1.852

4.829

< 0.001

NA

NA

NA

NA

  Quadrigeminal cistern

4.414

3.431

8.545

< 0.001

2.477

1.056

5.809

0.037

 IVH

2.793

1.711

4.559

< 0.001

NA

NA

NA

NA

 ICH

1.879

1.151

3.068

0.012

NA

NA

NA

NA

 Aneurysm locations

  PCoA aneurysm

0.590

0.318

1.094

0.094

NA

NA

NA

NA

  VA aneurysm

3.542

1.341

9.356

0.011

NA

NA

NA

NA

Severity of aneurysmal SAH on admission

 PAASH grade of III–V

14.771

8.894

24.531

< 0.001

10.868

4.281

27.592

< 0.001

 WFNS grade of IV–V

15.387

9.291

25.483

< 0.001

NA

NA

NA

NA

 H&H grade of IV–V

14.034

8.535

23.076

< 0.001

NA

NA

NA

NA

Aneurysm repairs and other treatments

 Aneurysm repairs

  No aneurysm repair

Reference

  

< 0.001

Reference

  

< 0.001

  Endovascular coiling

0.011

0.004

0.030

< 0.001

0.016

0.004

0.060

< 0.001

  Surgical clipping

0.023

0.009

0.062

< 0.001

0.030

0.008

0.105

< 0.001

 Nimodipine

0.071

0.027

0.191

< 0.001

0.193

0.030

1.232

0.082

Complications

 Rebleeding

6.133

2.138

17.594

0.001

27.870

5.748

135.118

< 0.001

 DCI

6.245

2.538

15.365

< 0.001

15.430

3.809

62.504

< 0.001

 Acute hydrocephalus

3.134

2.028

4.842

< 0.001

2.224

0.976

5.065

0.057

 Pneumonia

4.022

2.263

7.148

< 0.001

4.358

1.678

11.321

0.003

 Constant

    

2.253

  

0.413

  1. AOR adjusted odds ratio, CI confidence interval, DCI delayed cerebral ischemia, H&H Hunt and Hess, ICH intracerebral haemorrhage, IVH intraventricular haemorrhage, mRS modified Rankin Scale, NA not available, OR odds ratio, PAASH Prognosis on Admission of Aneurysmal Subarachnoid Haemorrhage, PCoA posterior communicating artery, SAH subarachnoid haemorrhage, VA vertebral artery, WFNS World Federation of Neurosurgical Societies.
  2. aEach variable of the demographics, risk factors for aneurysmal SAH, comorbidities, initial clinical, neuroimaging and laboratory characteristics, the severity of aneurysmal SAH (i.e., the grades of PAASH, WFNS, and H&H grading scales that were either greater than or equal to the cut-off value) on admission, treatments, and complications was analysed in the univariable logistic regression model and was considered in the multivariable logistic regression model if the p value was < 0.05 in univariable logistic regression analysis, as well as clinically crucial factors.
  3. bAll selected variables were included in the multivariable logistic regression model with the stepwise backward elimination method. Variables, then, were deleted stepwise from the full model until all remaining variables were independently associated with poor outcomes.
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